Endocrine Abstracts

It has been proposed that cellular Ca2+ signals activate hormone secretion. In pancreatic β cells, which produce insulin, Ca2+ signals have been known to contribute to insulin secretion. Prior to this study, we confirmed that Calbindin-D9k (CaBP-9k) was responsible for regulation of the distribution of free calcium in the cytoplasm. We also confirmed that insulin-secreting β cells express CaBP-9k, and assumed that CaBP-9k play a role in β c...